Phenergan (promethazine) is a common antihistamine used for allergy symptoms, nausea, motion sickness, and as a short-term sleep aid.

It also helps reduce anxiety before surgery and can ease migraine symptoms in some people. Because it sedates, expect drowsiness the first time you try it. Avoid driving or using heavy machinery until you know how it affects you.

Dosage varies by reason for use. Adults usually take 12.5–25 mg every 4 to 6 hours as needed, with a maximum daily dose often around 100 mg. Children require much lower doses and promethazine is not recommended under two years old due to serious breathing risks. Always follow your prescriber's instructions and check the label if you buy a pharmacy product.

Side effects to watch for include drowsiness, dry mouth, blurred vision, constipation, and confusion in older adults. Less common but serious effects are breathing difficulties, severe dizziness, fainting, or irregular heartbeat. Stop the drug and get medical help if you notice severe reactions. For elderly patients, this medicine can increase the risk of falls and low blood pressure.

Promethazine interacts with many drugs. Combining it with alcohol, opioids, benzodiazepines, or other sedatives boosts sedative effects and can be dangerous. Avoid mixing with MAO inhibitors or large doses of antihistamines. It can also increase the effects of certain antidepressants and antipsychotics. Tell your doctor about all medicines, supplements, and herbal products you use.

Pregnancy and breastfeeding require caution. Promethazine is sometimes used in pregnancy for severe nausea, but talk to your obstetrician before taking it. It passes into breast milk and may make a nursing infant drowsy. If you are pregnant or nursing, ask a specialist for a safer option.

Practical tips for safe use: keep a medication list with doses and reasons for each drug; set alarms for doses to avoid accidental double dosing; store promethazine away from children; never share your prescription; and use the lowest effective dose for the shortest time. If you plan air travel or long trips, pack a copy of your prescription and a note from your doctor.

If you prefer non-drug options for nausea or motion sickness, try ginger, acupressure wrist bands, or steady breathing techniques for mild cases. For severe or persistent vomiting, seek medical care promptly.

Want to buy Phenergan online? Use only licensed pharmacies that require a prescription. Be wary of sites selling sedatives without a prescription. Look for clear contact information, pharmacist access, and secure payment. When in doubt, ask your healthcare provider for approved pharmacy recommendations.

Overdose signs include extreme drowsiness, slow or shallow breathing, fainting, irregular heartbeat, or seizures. If you suspect an overdose call emergency services or your poison control center right away. Dispose of unused pills at medicine take-back sites. If a take-back isn't available, mix pills with an unwanted substance, seal them, and throw them away—don't flush.

If Phenergan causes too much sedation, ask your doctor about meclizine, ondansetron, or scopolamine patches for nausea and motion sickness.

For allergies, non-drowsy options like cetirizine or loratadine help.